Leslie Hiatt

Dr. Hiatt enjoys teaching students how to quantitate analytes and how to use instruments to analyze complex samples. She mainly teaches intro to chemistry general chemistry, quantitative analysis, and instrumental analysis. She additionally teach data analysis. General Chemistry is the first course a chemistry major takes and teaches students the basics needed in all levels chemistry. Quantitative Analysis teaches students how to develop good experimental protocols and then how to properly analyze data using numerical evidence. Instrumental Analysis builds on the skills developed in Quant to teach students how to use instruments to perform more advanced analysis of samples. The students in this course become experienced users of all the advanced instruments our department has to offer.

Our lab is working to understand the nicotine content and dangers associated with electronic cigarettes. Can consumers trust the labels that describe the amount of nicotine in each liquid refill bottle? Does the content vary across batches? Does it change significantly over time and after the liquid's expiration date? Does the process of vaping change the dangers of the eliquids?Our research utilizes electrochemistry and other instrumentation to answer these questions.

Additionally, our lab is interested in looking to determine new ways to quantitate and characterize carotenoids. Carotenoids are organic pigments that occur naturally in plants and other photosynthetic organisms. When you see the beautiful oranges, reds, and yellows of fall foliage; you are seeing a few of the vibrant colors associated with carotenoids. They are also the pigments you see in egg yolks and in colorful fish. This research is in the fields of bioanalytical electrochemistry, chromatography, and mass spectrometry.

• Monica. B. Pan, Macy L. Osborne, Autumn L. Maczko, Leslie A. Hiatt, Anuradha Liyana Pathiranage. "Utilizing HIV-1 Protease Inhibitor Drugs to Teach Drug Discovery and Molecular Modelling in the Organic Chemistry Lab" Chem. Educator. 2019, 24, 102-106.
• Jacob L. Williams, Taylor A. R. Oberman, Kristoffer L. Conrad, Martin E. Miller, Parth H. Patel, Meagan K. Mann, and Leslie A. Hiatt. "Inductive Data Analysis: A New Pedagogical Approach Using Simultaneous Methods of Quantitation" Chem. Educator 2018, 23, 179-185.
• Jacob Williams, Martin E. Miller, Brianna Avitabile, Dillon Burrow, Allison Schmittou, Meagan Mann, and Leslie Hiatt. "Teaching Students to be Instrumental in Analysis: Peer-Led Team Learning in the Instrumental Laboratory" J Chem Ed, 2017, 94(12), 1889-1895. DOI: 10.1021/acs.jchemed.7b00285.
• Danielle W. Kimmel, Mika E. Meschievitz, Leslie A. Hiatt, and David E. Cliffel. "Multianalyte Microphysiometry of Macrophage Responses to Phorbol Myristate Acetate, Lipopolysaccharide, and Lipoarabinomannan" Electroanal, 2013, 25, 1706-1712.
• Leslie A. Hiatt and David E. Cliffel. "Real time Recognition of Mycobacterium tuberculosis and Lipoarabinomannan using the Quartz Crystal Microbalance." Sens Actuators, B, 2012, 174, 245-252.
• Reese S. Harry, Leslie A. Hiatt, Danielle W. Kimmel, Clare K. Carney, Kristin C. Halfpenny, David E. Cliffel and David W. Wright. "Metabolic Impact of 4-Hydroxynonenal on Macrophage-Like RAW 264.7 Function and Activation." Chem Res Toxicol, 2012, 25, 1643-1651.
• Leslie A. Hiatt, Jennifer R. McKenzie, Leila F. Deravi, Reese S. Harry, David W. Wright, and David E. Cliffel. "A printed superoxide dismutase coated electrode for the study of macrophage oxidative burst." Biosens Bioelectron, 2012, 33, 128-133.
• Scott A. Miller, Leslie A. Hiatt, Robert G. Keil, David E. Cliffel, and David W. Wright. "Multifunctional nanoparticles as simulants for a gravimetric immunoassay" Anal Bioanal Chem, 2011, 399, 1021-1029.